TMS-Induced Seizure during FDA-Approved Bilateral DMPFC Protocol for Treating OCD: A Case Report

TMS-Induced Seizure during FDA-Approved Bilateral DMPFC Protocol for Treating OCD: A Case Report

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Repetitive transcranial magnetic stimulation (rTMS) is a noninvasive brain stimulation therapy that has become a method of choice for the treatment of several neuropsychiatric disorders such as depression and OCD.It is considered to be a safe and well-tolerated treatment, with only few side effects.The most serious adverse event during any rTMS treatment is the potential induction of a seizure.rTMS has shown very encouraging results for treatment-resistant lock shock and barrel art OCD, although the optimal target area and the stimulation frequency are still matters of controversy.

Here, we present a 19-year-old female patient with OCD who experienced seizure during the 7th session of her rTMS treatment using the FDA-approved 20-Hz protocol for OCD applied bilaterally over the left and right DMPFC using a double-cone coil.Nonetheless, it still unknown whether the seizure occurred as a consequence of rTMS, swisse high strength magnesium powder berry as the patient was also in a specific seizure risk group.Future reviews are needed to further clarify the mechanisms that may trigger seizures during rTMS treatments in order to reduce the likelihood of rTMS-induced seizures.